The diabetes It is a chronic disease that affects more than 400 million people around the world and more than 5 million people in Spain. It is currently being investigated whether the COVID-19 it could be a cause of this disease.
During the current COVID-19 pandemic It has been shown that the disease, caused by the SARS-CoV-2 virus, is not a mere infectious clinical picture with respiratory involvement. It is a pathology capable of producing a series of subsequent negative health effects of some of the patients who have suffered it.
If you want to know more about the relationship between Diabetes and the COVID-19 pandemic, below AmericanPost.News It shares information about this condition in patients infected with Coronavirus.
Can COVID-19 cause diabetes?
Recent data have confirmed a close association between SARS-CoV-2 infection and diabetes mellitus. The relationship between these two diseases appears to be bidirectional. On the one hand, it is widely demonstrated that diabetes mellitus is a poor prognostic factor in the evolution of the coronavirus.
Diabetics infected with SARS-CoV-2 have a higher risk of developing severe pneumonia, higher rates of hospital admissions, and higher mortality than non-diabetic subjects infected with SARS-CoV-2.
A recent meta-analysis showed that diabetes increases 2.3 times the risk of severity and 2.5 times the risk of mortality associated with the coronavirus.
The data obtained so far seem to indicate that the Coronavirus could be the cause of the increase in blood sugar levels of patients affected and therefore the appearance of diabetes mellitus.
How is the Coronavirus related to Diabetes?
The way that coronavirus disease could be related to diabetes is:
- Cytokine storm effect
Covid-19 produces a storm of pro-inflammatory cytokines such as interleukin 6 or IL-6 and IL-1beta, which have been shown to be related to the establishment and development of type 2 diabetes mellitus.
- Insulin-producing cell infection
On the other hand, in patients with covid-19, direct damage is observed on the pancreatic beta cells that produce insulin. The virus infects these cells that have the ACE2 membrane molecule on their surface, using it as a key to get inside.
- Induction of autoimmunity
As with other viral infections, infection of insulin-producing cells by SARS-CoV-2 can induce an autoimmune response against them. This could cause the immune system to mistakenly attack them, destroy them, and cause type 1 or insulin-dependent diabetes.
- Increased stress
The coronavirus increases stress throughout the body, which is accompanied by an increase in the production of stress-related hormones such as glucocorticoids, secreted by the adrenal glands. These hormones have among their multiple effects the elevation in blood glucose levels (hyperglycemia).
In conclusion, the appearance of diabetes in patients who have suffered covid-19 could be added, if subsequent studies confirm it, to the long list of pathological sequelae caused by this pandemic.
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